The Prader-Willi syndrome (PWS [MIM 17620]) and Angelman syndrome (AS [MIM 105830]) locus is controlled by a bipartite imprinting center (IC) consisting of the PWS-IC and the AS-IC. The most widely accepted model of IC function proposes that the PWS-IC activates gene expression from the paternal allele. while the AS-IC acts to epigenetically inactivate the PWS-IC on the maternal allel... https://safeersappliancers.shop/product-category/cookers/