The cohesin complex. which is essential for sister chromatid cohesion and chromosome segregation. also inhibits resolution of sister chromatid intertwinings (SCIs) by the topoisomerase Top2. The cohesin-related Smc5/6 complex (Smc5/6) instead accumulates on chromosomes after Top2 inactivation. https://proozya.shop/product-category/jeans/